CMD-003 consists of patient-derived (autologous) Epstein-Barr virus (EBV)-specific T cells. The T cells specifically target four EBV epitopes (LMP1, LMP2, EBNA1 and BARF1).
EBV infects more than 90% of the human population on a latent basis and is connected to a variety of cancers. CMD-003 has potential for the treatment of patients with non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) as well as nasopharyngeal carcinoma (NPC) and post-transplant lymphoproliferative disease (PTLD).
Cell Medica presented encouraging results of Phase II CITADEL trial with EBV specific T-cell product, baltaleucel-T (CMD-003), at the 2018 Annual SITC Meeting in Washington DC. (abstract P240, Poster)
We are actively exploring partnering opportunities for our EBV targeted T cell platform. Please see our Partnering page for contact information.