Dominant TCRs

Our T cell receptor (TCR) technology is currently in development and is a genetic approach to optimizing the function of TCRs.

The genes of the TCRs are isolated and modified before being introduced to T cells that would otherwise struggle to respond to the cancer or that lack a TCR capable of recognizing the cancer antigen.

We have developed a TCR construct that is capable of recognizing intracellular targets. We aim to optimize the activating capacity of the TCR to enhance anti-tumor activity.