Cell Medica is committed to transforming patients’ lives through developing the significant therapeutic potential of cellular immunotherapy for the treatment of cancer. We are advancing innovative cell-based therapies using proprietary technology platforms incorporating chimeric antigen receptors (CARs) and engineered T cell receptors (TCRs).
Our CAR-modified T cell products are being developed in collaboration with Baylor College of Medicine and University of North Carolina. Cell Medica’s differentiated approach utilises NKT cells (a subset of T cells) engineered to express IL-15 to maintain anti-cancer potency within the immunosuppressive tumour micro-environment. We are developing both autologous and allogeneic (off-the-shelf) products using the CAR-NKT cell technology.
In the field of engineered TCRs, we are working with University College London, to develop the Dominant TCR technology to improve the potency of TCR-modified T cells while maintaining the safety profile. Our product portfolio also includes baltaleucel-T (EBV-specific T cells) for the treatment of lymphomas associated with the Epstein Barr virus.